Photonics for future chemical sensing

Hot melt extrusion

HME has more recently been applied to the health care industry where it is used to manu facture medical devices and to mix active pharmaceutical ingredients (APIs) with polymers to enhance the API’s bioavailability or prepare precursors for thermoplastic drug eluting devices such as subcutaneous implants. Sentronic SentroPAT FO can be employed directly in the outlet port of the hot melt extruder in order to continuously assess product potency and content uniformity. This essential information can be used to assessment formulation and process design as well as critical quality attribute performance in real time.